Endocrine Abstracts

IntroductionRetinoids are a class of molecules, structurally related to Vitamin A, used in various disorders of keratinization (acne, psoriasis, ichthyosis, etc.). these molecules bind two families of Retinoid Nuclear Receptors (RNR): the RA receptors (RAR), which natural ligand is retinoic acid, and the Retinoid X Receptors (RXR), which natural ligand is 9-cis-retinoic acid. Among synthetic retinoids, isotretinoin, acitretin, tazarotene and ada...